Excited to announce the launch of SPRAVATO®..... Click Here to Learn More →
Excited to announce the launch of SPRAVATO®..... Click Here to Learn More →
Living with chronic pain impacts far more than your body—it can interfere with your sleep, strain your relationships, limit mobility, and take a heavy toll on your emotional well-being. For many, the search for lasting relief becomes a frustrating cycle of short-term fixes and disappointing results.
At Tennessee Ketamine & Wellness Center in Franklin, we provide a science-based, personalized solution for those who haven’t found success with conventional pain medications or therapies.
Our experienced medical team specializes in intravenous ketamine infusions that target the neurological root causes of chronic pain—offering many patients a real chance at long-term improvement in comfort, functionality, and overall quality of life.
Unlike opioids, which primarily mask pain signals, ketamine works differently—by addressing the actual neurochemical processes that drive chronic pain.
Many long-term pain conditions are associated with central sensitization, a condition in which the nervous system becomes hypersensitive and misinterprets normal signals as pain.
Ketamine is a potent NMDA receptor antagonist, meaning it blocks the receptors responsible for maintaining this heightened state of nerve excitation. By disrupting this feedback loop, ketamine helps reduce excessive glutamate activity, a key factor in pain amplification and emotional distress.
Through this mechanism, ketamine has been shown to “reset” malfunctioning pain pathways, helping to restore a more normal sensory experience. Unlike traditional painkillers, which can lead to tolerance or dependency, ketamine’s action works at the cellular level to promote healing and reduce chronic over-activation of the nervous system.
Clinical research supports its use for a variety of difficult-to-treat pain conditions. Patients at our Franklin clinic often report decreased pain intensity, better mobility, and improved sleep and mood—even after only a few sessions.
At Tennessee Ketamine & Wellness Center, we use ketamine therapy to treat a wide range of chronic pain conditions, particularly those that have proven resistant to traditional treatments. Some of the most common diagnoses we support include:
Chronic nerve pain—whether from diabetes, chemotherapy, physical trauma, or post-surgical damage—can feel like burning, stabbing, or electric shock sensations.
Standard medications often fall short, and many patients find themselves stuck in a cycle of partial relief.
Ketamine can calm overactive nerve pathways, reducing the abnormal signals that cause neuropathic pain. This effect may help restore quality of life and function for those living with ongoing nerve-related discomfort.
CRPS is a debilitating condition often triggered by injury or surgery, leading to severe pain, swelling, and changes in skin temperature or color. The pain is usually disproportionate to the initial injury and difficult to treat.
Ketamine helps interrupt the dysfunctional pain signaling loop involved in CRPS, decreasing both physical discomfort and the emotional toll it can take. Many CRPS patients experience improved mobility and function after a short series of infusions.
In addition to neuropathic pain and CRPS, ketamine may be used for other chronic pain syndromes such as fibromyalgia, tension-type headaches, certain types of migraines, and widespread musculoskeletal pain.
By working directly on the nervous system’s central pain pathways, ketamine helps reduce sensitivity and increase resilience to pain triggers.
Ketamine is not an opioid and does not carry the high risk of dependence, making it a safer long-term option for managing chronic pain.
Many patients begin to feel a noticeable reduction in pain symptoms after just one or two infusions. A full course of treatment often delivers even more dramatic results.
The effects of ketamine can last for several weeks or months following a treatment series, helping reduce reliance on daily medications and frequent doctor visits.
Every treatment plan at our Franklin clinic is uniquely designed. We adjust dosing, infusion frequency, and duration based on your specific diagnosis, pain level, and medical history to ensure optimal outcomes.
All ketamine infusions are administered in quiet, private treatment rooms under close medical supervision. We prioritize both safety and comfort, with compassionate care provided by trained professionals who understand chronic pain.
If chronic pain has left you feeling hopeless, isolated, or unable to enjoy the things you love, Tennessee Ketamine & Wellness Center in Franklin, TN offers a new approach that could transform your life.
We understand how exhausting it is to live with daily pain—and we’re here to help you explore a solution grounded in science, delivered with compassion, and tailored to your specific needs.
Contact us today to schedule your initial consultation and learn more about how ketamine therapy could offer the long-awaited relief you deserve.
Let us support you on your journey toward less pain, better function, and a renewed sense of possibility.
Conditions Treated
1909 Mallory Lane, Suite 300, Franklin, TN 37067