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When anxiety overwhelms your days—constant mental noise, tight muscles, that gnawing sense of unease—you deserve a treatment that works quickly and reliably.
At Tennessee Ketamine & Wellness Center, located in the heart of Franklin, we use carefully administered low-dose ketamine infusions to help reset the brain’s overactive fear and worry circuits.
Many of our patients begin to feel a noticeable lift in mood and a profound calm just hours after their very first treatment.
Ketamine works in a unique way by selectively blocking NMDA receptors in the brain. This action triggers a release of glutamate, a powerful neurotransmitter that activates brain regions linked to emotional regulation and fear response.
This surge jumpstarts the growth of new neural connections, helping to rewire the brain’s anxiety-prone pathways.
Unlike traditional anti-anxiety drugs such as SSRIs or benzodiazepines—which can take weeks to take effect or may lead to dependence—ketamine often delivers measurable relief within just two to four hours post-infusion.
Your care at Tennessee Ketamine & Wellness Center begins with an in-depth consultation. Our experienced providers will evaluate your anxiety symptoms, review your medical history, and understand your personal treatment goals.
When you return for your first infusion, you’ll relax in a quiet, comfortable room while ketamine is slowly administered through an IV over roughly 40 minutes.
Throughout the session and during your recovery period, our medical team closely monitors your heart rate, blood pressure, and mental state to ensure your safety and comfort.
Every detail—from our serene clinical environment to our expert protocols—is designed to make your experience as soothing and effective as possible.
We specialize in supporting individuals whose anxiety hasn’t responded to previous treatments, including therapy, prescription medications, or holistic approaches.
This also includes people struggling with severe, recurrent panic attacks that interfere with daily functioning.
Because ketamine can cause temporary spikes in blood pressure and mild dissociation, we conduct comprehensive cardiovascular screenings to ensure every patient is a safe candidate.
When used responsibly under medical supervision, ketamine can dramatically reduce both emotional and physical symptoms of anxiety, with effects lasting from several days to over a week after a single treatment.
To maintain the progress achieved, we typically recommend starting with an induction phase: two ketamine infusions per week for about two to four weeks.
After this foundational stage, many patients shift to maintenance infusions spaced out every two to four weeks.
For those seeking deeper healing, we also offer ketamine-assisted psychotherapy (KAP) in partnership with licensed mental health professionals. This powerful combination helps reinforce new neural pathways and develop sustainable coping skills during the period of increased brain plasticity ketamine creates.
Mild and temporary side effects—such as increased heart rate, lightheadedness, or a floating sensation—are common, but we manage these in real time during your visit.
Our infusions are administered at therapeutic (not recreational) doses, significantly reducing the risk of bladder or cognitive side effects.
Our Franklin-based team tailors every treatment plan to suit your medical profile and anxiety history—delivering meaningful relief in the safest, most personalized way possible.
If anxiety has taken hold of your daily life, you’re not alone—and you don’t have to keep suffering.
Tennessee Ketamine & Wellness Center in Franklin, TN is here to offer a new path to healing through the proven power of ketamine therapy.
Reach out to our care team today to schedule a consultation and take your first step toward a calmer, more centered you.
Most patients begin noticing a drop in anxious thoughts and body tension within two to four hours of their first session. This rapid onset distinguishes ketamine from traditional anti-anxiety medications, which can take weeks to show full results.
While every person responds differently, the benefits of a single ketamine infusion typically last between one and two weeks. To maintain progress, we usually recommend starting with multiple infusions during the initial induction period, followed by ongoing maintenance sessions.
Because ketamine can temporarily raise blood pressure, we perform a full cardiovascular screening before beginning treatment. If your hypertension is well-managed, you may still be eligible. We closely monitor your vitals throughout each session to ensure safety.
Some individuals report a sensation of light dissociation or feeling “floaty,” but these effects are brief and closely monitored by our trained staff. You remain awake and responsive during your infusion.
Symptoms may slowly reappear over time without maintenance treatments. That’s why we create a personalized follow-up plan tailored to your needs. Many patients successfully maintain their improvements with less frequent infusions and by integrating therapy to build stronger long-term coping mechanisms.
Conditions Treated
1909 Mallory Lane, Suite 300, Franklin, TN 37067
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RN & Clinical Manager
Trina Haag is a highly experienced and compassionate Registered Nurse with over 15 years of expertise in patient care and advocacy. Her diverse background includes roles as a Medical Assistant, Phlebotomist, and Registered Nurse specializing in ICU and perioperative care. In addition to her clinical skills, Trina has successfully managed medical offices, where she excelled in delivering exceptional customer service and personalized patient care.
Trina’s commitment to patient advocacy is evident through her involvement with the National Patient Advocacy Foundation, where she passionately supports patient rights and quality healthcare. Her dedication to individualized care ensures that every patient at TNKWC receives the highest level of compassionate and personalized treatment.
Outside of her professional life, Trina values time spent with her family, including her loving husband, her daughter who brings joy to her days, and their loyal furry friend.[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/2″][us_image image=”568″ style=”shadow-2″][us_separator][us_btn label=”Schedule A Consultation” link=”url:%2Fcontact%2F|title:Contact” width_type=”1″][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row]
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Dr. Rachel Rome is a board-certified anesthesiologist and interventional pain specialist with a deep expertise in regenerative medicine and palliative care. Her commitment to individualized patient care, innovative treatment approaches, and her prioritization of utilizing a holistic approach has made her a respected figure in the medical community.[/vc_column_text][vc_column_text]Witnessing the transformative impact of ketamine on patients suffering from depression and chronic pain, Dr. Rome pursued advanced training in ketamine administration. In November 2021, she founded Mindful Infusions of TN, a concierge ketamine and wellness clinic, where she served as Medical Director. In addition, she has had the privilege of serving the local community at several clinics including David Price Regenerative Medical Center, LifeLinc Pain, and Empatia Palliative Care.
Dr. Rome earned her undergraduate degree in biology from Christian Brothers University and her medical degree from the University of Tennessee College of Medicine in Memphis. She completed her residency in anesthesiology and a fellowship in pain management at the University of Virginia in Charlottesville. She is an active member of the American Society of Anesthesiologists and the American Society of Interventional Pain Physicians.[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/2″][us_image image=”599″ style=”shadow-2″][us_separator][us_btn label=”Schedule A Consultation” link=”url:%2Fcontact%2F|title:Contact” width_type=”1″][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row]
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Dr. Malchow served as an anesthesiologist for 25 years in the armed forces before retiring as a colonel in 2008. He then became an associate professor at Vanderbilt University Medical Center in Nashville, where he was the first Vanderbilt physician to offer intensive ketamine infusion therapy in 2014. In 2015, he established one of the few ketamine infusion centers (KIC) in the Veteran Health Administration and the only KIC in the U.S. specifically targeting opioid cessation/reduction.
He is an acknowledged U.S. expert on ketamine administration, having presented his extensive experience with ketamine in the veteran population at the American Society of Ketamine Physicians in 2018 and has given multiple lectures regarding the use of ketamine to national audiences in 2021. Dr. Malchow has published over 20 peer-reviewed journal articles and serves regularly on worldwide medical missions supporting those in need.
Dr. Malchow is honored to serve as the Medical Director for the Tennessee Ketamine & Wellness Center to provide compassionate and competent care for those suffering from depression, PTSD, OCD, chronic pain, and opioid dependence.[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/2″][us_image image=”162″ style=”shadow-2″][us_separator][us_btn label=”Dr. Malchow’s Full CV” link=”url:%2Fwp-content%2Fuploads%2F2021%2F06%2F03-2021-Malchow-CV.pdf|target:_blank” width_type=”full” icon=”fas|file-alt”][us_btn label=”Schedule A Consultation” link=”url:%2Fcontact%2F|title:Contact” width_type=”1″][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row]