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SPRAVATO® Nasal Spray Therapy at Tennessee Ketamine & Wellness Center

Experience a New Path Forward: SPRAVATO® for Depression Relief in Tennessee

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What Is SPRAVATO®?

SPRAVATO® (esketamine) is a groundbreaking nasal spray approved by the FDA for adults struggling with two challenging types of depression:

depression

Treatment-Resistant Depression (TRD): Designed for individuals who have not responded to at least two different antidepressants.

ptsd

Major Depressive Disorder (MDD) with Acute Suicidal Ideation or Behavior: A rapid-acting option for individuals experiencing intense symptoms and an urgent need for stabilization.

Unlike traditional oral antidepressants that may take weeks to work, SPRAVATO® has been shown to deliver symptom relief in as little as 24 hours.

FDA-Approved

Insurance-covered

fast-acting

How SPRAVATO® Works

SPRAVATO® operates differently from standard treatments by acting on NMDA receptors in the brain. This novel approach helps reset neural pathways that contribute to depression. Administered in our certified treatment center at Tennessee Ketamine & Wellness Center, patients self-administer the nasal spray under clinical supervision and remain on-site for observation for a minimum of two hours to ensure safety.

spravato treatment near me, TN

What Our Patients Are Saying

insurance and treatment near me

Now Accepting Insurance

We work with many major insurance providers to help make SPRAVATO® accessible to our patients.

Your 4-Stage SPRAVATO® Experience at TKWC

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Consultation and Eligibility Review

Start with a paid phone consultation, with the cost applied toward your infusion if you move forward with treatment. If eligible, you'll meet with our mental health professionals for a full evaluation and medical history review. We’ll also verify insurance coverage to avoid surprises.

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Scheduling and Supervised Administration

After approval, your SPRAVATO® sessions will be scheduled at our clinic. You’ll self-administer the spray in a calm, comfortable environment while monitored by our staff for at least two hours.

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Personalized Treatment Planning

Treatment begins with an induction phase (typically two sessions weekly) and transitions to maintenance dosing. We customize frequency based on your individual progress and needs.

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Ongoing Care and Support

Our care team is with you every step of the way. We offer regular follow-ups, collaborate with your existing mental health providers, and continuously adapt your care plan.

SPRAVATO® Treatment Phases

induction
Induction

Week 1-4
2 Treatments a Week

maintenance
maintenance

Week 5-8
1 Treatments a Week

ongoing care
ongoing care

Week 9+
1 Treatments a Week Every 1-2 Weeks

Why Choose SPRAVATO® Over Traditional Antidepressants?

Response Rate:
Conventional antidepressant medications generally yield positive treatment responses in about 40% to 60% of patients. In contrast, clinical research on SPRAVATO® (esketamine) has reported response rates reaching up to 70% (Popova et al., 2019, American Journal of Psychiatry).

Onset of Therapeutic Effect:
Whereas standard antidepressants may require between four to six weeks before users begin to notice any significant improvement, esketamine (SPRAVATO®) has been associated with symptom relief in as little as 24 hours, according to clinical trial data (BMC Psychiatry, 2022).

Sustained Remission Rates:
In a clinical trial, 43.8% of individuals who continued treatment with Spravato alongside an oral antidepressant at the three-month mark had entered remission from major depressive episodes.

Response Rate

response rate

Time to Noticeable Effect

time to noticeable effect

Sustained Remission Rate

remission rate

Why Patients Trust Tennessee Ketamine & Wellness Center

safety first

Safety Is Our Foundation:

We follow only FDA-approved treatment protocols.

setting as cure

Healing Environment:

Our clinic spaces are designed to support mental wellness.

talking to your team

Coordinated Care:

We engage your existing care team to ensure consistent and holistic support.

accessibility for all

Simplified Access:

We work with your insurance and handle all necessary paperwork.

SPRAVATO® FAQs

Tell your provider about your full health history, medications, any substance use, and if you’re pregnant or breastfeeding.
SPRAVATO® is an FDA-approved nasal spray containing esketamine. IV ketamine is a different formulation often used off-label.

No. SPRAVATO® must be administered in a clinical setting under supervision.

Generally not recommended. Consult your provider for guidance.
Individuals with a history of aneurysms, certain vascular disorders, or esketamine allergies should speak with their provider first.
You may notice mood improvements and functional gains. Your provider will use structured assessments to track progress.
Contact the clinic as soon as possible to reschedule.
Yes. All of your healthcare providers should know about your SPRAVATO® treatment.
Your provider may adjust your regimen or explore other options if results are limited.
Possibly. Blood pressure will be monitored closely at each session.
Yes. Please share all current medications with your provider to reduce interaction risks.
Avoid food for two hours and liquids for 30 minutes before treatment.
You should not drive or operate machinery for the remainder of the day.

SPRAVATO® Educational Tools

Download our informational materials to learn more about SPRAVATO® and how it may benefit your recovery journey.

Schedule A Consultation

We know how busy life can be, so we offer the option of contacting you based on your preferences to discuss Ketamine Infusion Therapy. Please provide your information below and we will contact you in the timeframe that you choose.